15437 Toxic Shock Syndrome
Informed by recognized medical guidance
Overview
A rare but very serious illness caused by bacteria releasing poisons (toxins) into the bloodstream. It can get worse quickly and needs urgent medical care.
Key facts
- Toxic shock syndrome (TSS) is a medical emergency.
- It is most often linked to tampon use, but can also happen after wounds, surgery, or childbirth.
- Early treatment in hospital greatly improves the chance of a full recovery.
No. Toxic shock syndrome is very rare. Most doctors may see only one or two cases in their whole career.
Anyone can get TSS, but it is most common in young women who use tampons, especially if they are left in too long. It can also affect men, children, and older adults after skin infections, burns, or surgery.
Symptoms
- High fever with a rash that spreads quickly
- Fainting, dizziness, or a feeling of passing out
- Severe confusion or difficulty waking
- Trouble breathing
- Vomiting that will not stop
- ⚠If you have a tampon or menstrual cup in place and develop a fever, rash, vomiting, or diarrhea — remove it and get medical help the same day.
- ⚠If you have a wound that is red, swollen, or leaking fluid and you feel generally unwell with fever or chills.
Common symptoms
- Sudden high fever (often over 102°F or 39°C)
- A sunburn-like rash on the palms and soles
- Low blood pressure (feeling dizzy or faint)
- Severe muscle aches
- Vomiting or diarrhea
- Redness in the eyes, mouth, or throat
- Confusion or feeling very sleepy
Symptoms in children
- High fever with a rash
- Being unusually irritable or drowsy
- Vomiting or diarrhea
- Floppy or weak body, difficulty feeding
Symptoms in older adults
- Confusion or memory problems
- Dizziness or falls from low blood pressure
- Sudden weakness or fatigue
- Rash that may be harder to see on older skin
Causes
Main causes
- Staphylococcus aureus (staph) bacteria producing toxins
- Streptococcus pyogenes (strep) bacteria producing toxins
- Bacteria getting into the bloodstream through a wound, burn, or the vagina during tampon use
Risk factors
- Using super-absorbent tampons or leaving tampons in for too long
- Using menstrual cups, cervical caps, or contraceptive sponges
- Recent surgery, childbirth, or miscarriage
- Skin wounds, burns, or cuts that become infected
- Viral infections like flu or chickenpox that make the body more vulnerable
When to see a doctor
See a doctor urgently if:
- Any of the emergency symptoms listed above — call your local emergency number now.
- If you have used tampons or a menstrual cup and develop a fever or rash, remove it and go to urgent care immediately.
Book a routine appointment if:
- If you have a wound that is not healing or looks infected and you feel unwell, make an urgent GP appointment.
- If you have concerns about TSS after using tampons or after surgery, talk to your doctor for advice.
Diagnosis
Doctors diagnose TSS based on your symptoms and a physical exam. Because it develops quickly, they will usually start treatment before all test results come back.
Tests that may be done
- Blood tests to check for infection and organ function
- Urine tests to look for kidney problems
- Swabs taken from the throat, vagina, cervix, or wounds to look for the bacteria
- Imaging such as a chest X-ray if needed
What to expect at your appointment
You will likely be admitted to hospital, and may be monitored in an intensive care unit (ICU) if your blood pressure is low. The care team will ask about tampon use, wounds, surgery, and other risk factors.
Treatment
Toxic shock syndrome is always treated in hospital, often in intensive care. Treatment focuses on removing the source of the bacteria, giving fluids and medicines to support blood pressure, fighting the infection, and supporting any organs that may be failing.
Self-care at home
- Remove any tampon, menstrual cup, diaphragm, or contraceptive sponge right away.
- Clean any wound or burn with soap and water and cover it with a sterile dressing.
- Do not attempt to treat TSS at home — you must go to hospital.
Medical treatments
Medical treatment usually includes intravenous (IV) fluids, antibiotics given directly into a vein, medicines to raise blood pressure, and sometimes immunoglobulin therapy (antibodies given through a drip) to neutralise the toxins. Oxygen or a breathing machine may be needed if lungs are affected. Dialysis may be used if the kidneys stop working.
When is surgery considered?
In some cases, surgery is needed to drain an abscess, remove infected tissue, or clean a deep wound. This helps get rid of the source of the toxins.
Living with this condition
Recovery from TSS can take several weeks. You will need rest, regular follow-up appointments, and time for your strength to return. Your doctor may advise avoiding tampons for a period of time.
Lifestyle tips
- Use sanitary pads instead of tampons or menstrual cups while recovering, and for as long as your doctor advises.
- If you go back to using tampons, use the lowest absorbency you need and change them every 4–8 hours.
- Keep any wounds clean, dry, and covered until healed.
Diet and exercise
Eat a balanced diet with plenty of fluids to help your body heal. Start with light activities like short walks, and build up gradually. Listen to your body and rest when you feel tired.
Mental health and emotional wellbeing
A serious illness like TSS can be frightening and emotionally draining. You may feel anxious, low, or have bad memories of the experience. These feelings are normal, and talking to a counsellor or support group can help.
Prevention
You can reduce your risk by using sanitary products carefully, changing tampons frequently, using the lowest absorbency needed, and keeping wounds clean and covered.
Vaccines
There is no vaccine against toxic shock syndrome.
Screening programmes
There is no routine screening test for TSS. Being aware of the symptoms and acting quickly is the best protection.
Complications
If left untreated
- Septic shock (a dangerous drop in blood pressure)
- Organ failure, including kidney, liver, or heart failure
- Skin breakdown or gangrene that may lead to amputation
- Death in severe cases
Long-term outlook
With early hospital treatment, most people with TSS recover fully. Some may need a longer recovery or have lasting effects, but acting quickly gives you the best chance of a full return to health. Survivors can go on to live normal, healthy lives.
Find support
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Always verify with your doctor
Health guidelines vary by country and region. The information in this article is based on international clinical guidelines but may not reflect the specific guidelines, medications, or practices in your country. Always discuss your health concerns with your own doctor or healthcare provider, and refer to your local national health guidelines where available.
Important notice This information is for educational purposes only. It does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider about your specific situation. If you are experiencing a medical emergency, call your local emergency services immediately.
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Sources and guidance
This article is educational and is prepared with reference to recognized health information and clinical guidance sources where available. Specific source links may vary by topic.
Last updated: July 31, 2026
Educational note: This information is for education only and is not a diagnosis.
Use it to support, not replace, advice from a licensed clinician.
If symptoms are severe, worsening, or urgent, call your local emergency number or seek emergency care.