Lipschutz Ulcer
Overview
Lipschutz ulcer is a painful sore that can appear on the outer female genital area, especially the labia (the lips of the vulva). It is also called acute genital ulcer. It is not a sexually transmitted infection (STI). It often happens during or after a viral illness and usually heals with supportive care.
Key facts
- Lipschutz ulcers are painful genital sores that are not caused by sexual activity.
- They are often linked to a recent infection, especially Epstein-Barr virus (EBV), the virus that causes glandular fever.
- Most heal in a few weeks, but a healthcare provider should check any new genital ulcer to rule out other causes.
It is uncommon. Many healthcare providers may never see a case, so it can take time to recognise. It is not a sign that you or your child has done something wrong.
It most often affects young women and girls, especially before age 20, but it can affect other people too. It can happen to people who have never been sexually active.
Symptoms
- Severe bleeding from the ulcer that does not stop
- Signs of a serious infection such as confusion, very fast breathing, cold or clammy skin, or fainting
- Complete inability to pass urine with lower belly pain or swelling
- ⚠High fever or feeling very unwell
- ⚠Severe pain that is not controlled with simple pain relief
- ⚠Cannot pass urine or only pass small amounts with severe pain
- ⚠Spreading redness, pus, foul smell, or worsening sores
- ⚠Signs of dehydration such as dizziness, dry mouth, or passing very little urine
Common symptoms
- One or more painful sores on the vulva, often round or oval with a red edge and a pale or grey centre
- Pain or burning when passing urine
- Fever or flu-like feeling
- Swollen tender glands in the groin
- Vaginal discharge in some cases
- Pain during walking, sitting, or sex
Symptoms in children
- It is rare in children but can occur, mainly in girls.
- A child may cry or complain of pain when passing urine, refuse to use the toilet, or have fever.
- Seek same-day medical advice if a child cannot pass urine, has a high fever, or has severe genital pain.
Symptoms in older adults
- It is rare after menopause.
- A new genital ulcer in an older adult should be checked promptly because other causes are more likely at this age.
Causes
Main causes
- Often linked to a recent infection, especially Epstein-Barr virus (EBV), the virus that causes glandular fever.
- Sometimes linked to other infections, such as mycoplasma or other viruses and bacteria.
- Sometimes no clear cause is found. It may be an immune reaction that causes inflammation and sores.
- It is not caused by sexual activity and is not classed as a sexually transmitted infection.
Risk factors
- Being a young woman or girl, especially under age 20
- A recent viral illness or glandular fever
- Changes in the immune system
- Having never had sex does not rule it out and is common in reported cases
When to see a doctor
See a doctor urgently if:
- You cannot pass urine or passing urine is extremely painful
- You have a high fever or feel very unwell
- The ulcer is getting bigger, spreading, or looks infected
- You have severe pain that is not controlled with simple pain relief
Book a routine appointment if:
- You notice any new genital ulcer for the first time
- Ulcers keep coming back
- An ulcer is not healing after a few weeks
- You want to be checked for STIs or other causes of genital ulcers
- You feel worried or embarrassed and want advice
Diagnosis
A healthcare provider will ask about your symptoms, recent illnesses, and medical history. They will look at the sores. They may take a swab from the ulcer and arrange blood tests to check for infections such as EBV and to rule out STIs. The diagnosis is usually made from the pattern of symptoms and test results.
Tests that may be done
- A swab from the ulcer to check for infections
- Blood tests for Epstein-Barr virus and other infections
- Urine tests
- Tests for sexually transmitted infections, even if you are not sexually active, because some can cause similar sores
- A small biopsy (tissue sample) if the diagnosis is unclear or the ulcer does not heal
What to expect at your appointment
The examination can feel uncomfortable or embarrassing. You can ask for a chaperone, a female clinician if available, and to stop at any time. The tests are usually quick. Results may take a few days. Your provider will explain what they find and what to do next.
Treatment
Treatment focuses on easing pain, helping the sores heal, and treating any infection that is found. Most people do not need surgery. Your healthcare provider will advise what is safe for you.
Self-care at home
- Take simple pain relief as advised by your pharmacist or healthcare provider
- Use cool compresses or a shallow warm bath to soothe the area and make passing urine less painful
- Wear loose cotton underwear and avoid tight clothing
- Keep the area clean with plain water and avoid scented soaps, wipes, or douches
- Drink plenty of fluids to keep urine less concentrated
- Avoid scratching or rubbing the sores
- Rest and give your body time to heal
Medical treatments
Your healthcare provider may suggest pain relief, soothing creams or gels, and treatment for any infection that is found. In severe or recurrent cases, they may refer you to a specialist. Antibiotics are only used if a bacterial infection is confirmed. Do not use leftover medicines or share medicines with others.
When is surgery considered?
Surgery is not usually needed for Lipschutz ulcers. In rare cases, a specialist may advise a procedure if there is a complication such as scarring or ongoing problems.
Living with this condition
The sores can be painful for a week or two, and some people feel tired or feverish. Plan rest, use pain relief as advised, and avoid activities that rub or irritate the area. Most people start to feel better within a few days to weeks.
Lifestyle tips
- Choose loose, soft clothing and cotton underwear
- Avoid scented products, harsh soaps, and vaginal douches
- Do not scratch or pick at the sores
- Wash your hands before and after touching the area
- Use a gentle laundry detergent and rinse underwear well
- Ask for help with childcare, work, or daily tasks if you feel unwell
Diet and exercise
There is no special diet for Lipschutz ulcers. Eat and drink normally, and drink enough fluids. Gentle activity is fine if you feel able. Rest when you feel tired or feverish. Avoid intense exercise that rubs the genital area until the sores are less painful.
Mental health and emotional wellbeing
Genital ulcers can feel embarrassing, worrying, or isolating. It is normal to feel upset. You do not have to cope alone. If you feel overwhelmed, anxious, or have thoughts of harming yourself, contact your local crisis support service or emergency services right away.
Prevention
There is no sure way to prevent Lipschutz ulcers. Good general health, treating infections promptly, and getting any genital ulcer checked early can help you get the right care. Practising safer sex helps protect against STIs, although it does not specifically prevent Lipschutz ulcers.
Vaccines
There is no vaccine specifically for Lipschutz ulcers. Keep up with routine vaccines as advised by your local health service.
Screening programmes
There is no routine screening test for Lipschutz ulcers. See a healthcare provider if you notice any genital ulcer or unusual pain.
Complications
If left untreated
- Ongoing pain and difficulty passing urine
- Dehydration if pain stops you drinking or passing urine
- A secondary bacterial infection of the sores
- Scarring or sticking together of the labia in rare cases
- Recurrence of ulcers in some people
Long-term outlook
Most Lipschutz ulcers heal with supportive care and do not cause lasting problems. Some people get them more than once, but they can be managed. Because the condition is not an STI, it does not mean you or your child has an infection from sexual contact. Seeing a healthcare provider helps rule out other causes and get the right support.
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Always verify with your doctor
Health guidance differs by country and region. This page is general education and may not match the guidelines, medicines, or practice where you live. Discuss your concerns with your own doctor or healthcare provider, and follow local guidance where it exists.
Important notice This information is for educational purposes only. It does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider about your specific situation. If you are experiencing a medical emergency, call your local emergency services immediately.
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Sources and guidance
No guideline names this topic
No health guideline or clinical chapter that names this exact topic is cited here. This page is for general education and information only. It is not a diagnosis, a treatment plan, or personal medical advice. Check with your own doctor and follow their advice. If symptoms are severe, sudden, or worrying, get medical care promptly, and call your local emergency number in an emergency. Ruqelo LLC is not responsible for medical or legal outcomes from decisions based on this information.
Last updated: October 24, 2026
Educational note: This information is for education only and is not a diagnosis.
Use it to support, not replace, advice from a licensed clinician.
If symptoms are severe, worsening, or urgent, call your local emergency number or seek emergency care.
Guidance may differ by country or region. Confirm local recommendations with a qualified healthcare provider.