Locomotor System
Overview
Your locomotor system — also called the musculoskeletal system — is the framework that lets you move and holds you together. It includes your bones, the joints where bones meet, your muscles, and the tough cords that connect them: tendons (which join muscle to bone) and ligaments (which join bone to bone). Cartilage is the smooth padding that covers the ends of bones inside joints. Together these parts give your body its shape, let you walk, lift, bend and stretch, protect your inner organs, and store minerals like calcium. When any part of this system is injured, worn, inflamed or weakened, you can feel pain, stiffness, swelling or a loss of movement.
Key facts
- The locomotor system is made up of bones, joints, muscles, tendons, ligaments and cartilage — about 206 bones and more than 600 muscles in an adult body.
- Problems with bones, joints and muscles are one of the most common reasons people visit a doctor, and most improve with rest, gentle movement and time.
- Keeping active, staying at a healthy weight and building muscle strength all help protect your locomotor system at every age.
Very common. Almost everyone has muscle aches, back pain, a sprain or joint stiffness at some point. Conditions like osteoarthritis (wear-and-tear of the joints) and back pain affect millions of people worldwide and are among the leading causes of time off work and reduced activity.
Everyone, at every age. Children and teenagers can have growing-related aches, sports injuries and posture issues. Working-age adults often have strains, overuse injuries and back or neck pain. Older adults are more likely to have joint wear, bone thinning (osteoporosis) and muscle loss, which can raise the risk of falls. Some inflammatory joint conditions are more common in women, and some are more common in men.
Symptoms
- A serious injury such as a fall from height or a road traffic crash, especially with a deformed or bent limb, bone showing through the skin, or severe bleeding
- Back pain together with numbness around the groin and buttocks, loss of bladder or bowel control, or weakness in both legs — this needs emergency assessment
- A hot, extremely painful, swollen joint together with a high fever, shivering or feeling very unwell
- Sudden severe pain and swelling in a leg or arm after an injury, with pale, cold or blue skin, or numbness — this could mean the blood supply is affected
- Chest pain, shortness of breath or collapse after an injury
- ⚠A joint or limb that swells up quickly after an injury, or that you cannot move or put weight on
- ⚠Fever with a swollen, hot joint
- ⚠Calf or thigh pain with swelling, warmth or redness, especially after long travel or surgery — this needs checking the same day
- ⚠New numbness, tingling or weakness in an arm or leg
- ⚠Pain that is getting much worse despite rest and simple pain relief
- ⚠A child who is limping, has a swollen joint, or refuses to walk
Common symptoms
- Pain in a bone, joint or muscle that may be sharp, dull, aching or throbbing
- Stiffness, especially after resting or first thing in the morning
- Swelling, warmth or redness around a joint or injured area
- Reduced movement — not being able to bend, straighten, twist or lift as usual
- Weakness or a feeling that a limb might 'give way'
- Muscle cramps, spasms or twitching
- Clicking, creaking or grinding sounds in a joint
- Tenderness when you press on the area
- Back or neck pain, sometimes spreading to the arms or legs
- Tiredness or a general feeling of being unwell when inflammation is present
Symptoms in children
- Limping or refusing to put weight on a leg
- Crying or pulling away when an arm or leg is touched or moved
- Being unwilling to use an arm — for example, not reaching for toys
- Aches in the legs at night, often around the knees or calves, which are usually harmless 'growing pains'
- Clumsiness or a change in how your child walks or runs
- Swelling or warmth around a joint, or a joint that looks different from the other side
Symptoms in older adults
- Joint stiffness and pain that builds up slowly over months or years
- Muscle weakness and loss of muscle bulk, which can make stairs and chairs harder
- Problems with balance and a higher chance of falls
- Loss of height or a stooped posture, which can be linked to bone thinning
- Pain that is worse with activity and eases with rest, or vice versa in inflammatory conditions
- Swelling in the knees, hips or hands
Causes
Main causes
- Injury — sprains, strains, bruises, dislocations and broken bones from falls, sport or accidents
- Wear and tear of joints over time, known as osteoarthritis
- Inflammation of joints or surrounding tissues, as in rheumatoid arthritis or gout
- Overuse from repeated movements at work, in sport or in daily tasks, such as tennis elbow or carpal tunnel problems
- Poor posture or awkward lifting, which can strain the back and neck
- Age-related changes in bones, muscles and cartilage
- Muscle weakness and inactivity, which leave joints less well supported
- Infection in a joint, bone or muscle (rare but serious)
- Conditions that affect the whole body, such as thyroid problems, or long-term use of some medicines such as steroid tablets
- Genetic factors — some joint and bone conditions run in families
Risk factors
- Getting older
- Being overweight, which puts extra load on hips, knees and the lower back
- A previous injury to the same joint or muscle
- A job or sport that involves repeated lifting, twisting, impact or long periods in one position
- Not being physically active, or sudden bursts of activity when you are not used to it
- Smoking, which slows healing and reduces bone and muscle health
- Family history of joint or bone conditions
- Being low in vitamin D or calcium, which weakens bones
- Long-term use of steroid medicines
- Being female and past the menopause, when bone strength can drop
When to see a doctor
See a doctor urgently if:
- You have had a serious injury, or you cannot use or put weight on the affected limb
- A joint is hot, very swollen and you also have a fever
- You have new numbness, tingling or weakness in an arm or leg
- You have back pain with numbness around the groin or trouble controlling your bladder or bowel
- One leg or arm is swollen, warm and painful without a clear cause
- Pain is severe, waking you at night, or getting worse rather than better
Book a routine appointment if:
- Pain or stiffness has lasted more than a few weeks or keeps coming back
- A joint is swollen or looks different from the other side
- Movement in a joint is limited or you feel it catching or locking
- Symptoms are affecting your work, sleep, exercise or daily tasks
- You have had several falls, or you feel unsteady on your feet
- You are worried about your symptoms or about a family history of joint or bone problems
Diagnosis
Your doctor will usually start by asking about your symptoms — when the pain began, what makes it better or worse, whether you have had injuries, and how it affects your daily life. They will then examine you, watching how you move and gently feeling your joints and muscles to check for swelling, tenderness, weakness or limited movement. Often this is enough to give you a clear answer and a plan. If more detail is needed, they may arrange tests.
Tests that may be done
- X-rays to look at bones and joints
- Ultrasound scans to check tendons, ligaments, muscles and fluid around a joint
- MRI scans for a detailed view of soft tissues, cartilage and the spine
- Blood tests to look for inflammation or other conditions affecting the joints
- Removing and testing a small sample of fluid from a swollen joint
- Bone density scanning to check bone strength if osteoporosis is a concern
- Nerve tests if you have numbness or tingling in an arm or leg
What to expect at your appointment
Most people get an answer after a simple examination, sometimes with an X-ray. Tests are usually quick and painless, and you can often go home the same day. If your doctor refers you to a physiotherapist or a specialist, there may be a wait — ask what you can do in the meantime to keep comfortable and stay mobile.
Treatment
Treatment depends on what part of the locomotor system is affected and why. Often the first steps are simple: resting the area briefly, using ice or heat, and then gently getting moving again. Physiotherapy is a key treatment for many muscle, joint and back problems, because stronger, more flexible muscles support and protect your joints. Medicines can help with pain and inflammation. Surgery is only needed for certain problems.
Self-care at home
- Rest the sore area for a short time, but avoid staying still for too long — gentle movement helps healing
- Use an ice pack wrapped in a cloth for the first couple of days after an injury, then heat if it feels comforting
- Raise a swollen limb, and use a supportive bandage if advised
- Try gentle stretching and movement within a comfortable range
- Ask your pharmacist about over-the-counter pain relief that is suitable for you
- Keep to a healthy weight to reduce strain on your hips, knees and back
- Set up your desk, chair and screen so you are not straining your neck or back
- Build muscle and balance with regular activity such as walking, swimming or strength exercises
- Get enough sleep — tiredness makes pain feel worse
Medical treatments
Your doctor may suggest pain-relieving or anti-inflammatory medicines, and your pharmacist can advise on what is safe for you, especially if you have other health conditions or take other medicines. Physiotherapy uses exercise, hands-on treatment and advice to improve strength and movement. Occupational therapists can suggest ways to make daily tasks easier. Some people benefit from injections into a joint or around a tendon, from a splint or brace, or from a referral to a specialist service such as rheumatology, orthopaedics or pain management. Treatment is tailored to you, so ask your healthcare team why a particular option is being suggested and what the alternatives are.
When is surgery considered?
Surgery is only considered when other treatments have not helped enough, or for specific problems such as a broken bone that needs fixing, a torn ligament or tendon, a badly damaged joint that could be replaced, or a trapped nerve. Your specialist team will explain the benefits and risks and help you decide.
Living with this condition
Living with a long-term muscle or joint problem usually means finding a steady rhythm: pacing your activities, breaking tasks into smaller steps, and mixing movement with rest. Many people find that a little activity every day works better than a big burst followed by days of pain. Practical changes — a firmer chair, a cushion, a trolley for shopping, a gripper for jars — can make a real difference. Plan ahead for tasks that strain you, and ask for help when you need it.
Lifestyle tips
- Stay active in a way you enjoy — walking, swimming, cycling, tai chi or gardening all count
- Add gentle strength work a couple of times a week to support your joints
- Take breaks from sitting and change position often
- Keep to a healthy weight
- Wear supportive, comfortable shoes
- Warm up before exercise and build up slowly
- Stop and rest if pain is sharp or getting worse, rather than pushing through
- Consider quitting smoking — it helps healing and bone health
Diet and exercise
A balanced diet with enough protein, calcium and vitamin D supports bones and muscles. Oily fish, dairy or fortified alternatives, pulses, eggs and plenty of vegetables are good everyday choices. If you are unsure whether you get enough vitamin D, especially in winter or if you cover your skin or stay indoors, ask your GP or pharmacist. For exercise, aim for something most days if you can: gentle movement when you are sore, and a mix of aerobic activity, strength work and balance work when you are able. A physiotherapist can help you find exercises that suit your body.
Mental health and emotional wellbeing
Ongoing pain and reduced movement can be tiring, frustrating and isolating. It is very common to feel low, anxious or worn down, and it is not a sign of weakness. Talking about how you feel often helps, and support is available — tell your doctor if your mood is affected, because pain and mood are closely linked and both can be treated. If you ever feel unable to cope or have thoughts of harming yourself, please contact your local emergency number or a crisis support service in your country straight away.
Prevention
Not all locomotor problems can be prevented, but you can lower your risk. Regular movement, strength and balance work, a healthy weight, good posture and safe lifting all protect your bones, joints and muscles. Warm up before exercise and build up gradually. Wear suitable footwear and use good equipment for sport. At work, adjust your chair, screen and task setup, and take regular breaks. Make sure you get enough calcium and vitamin D, and ask your doctor about bone health if you have risk factors such as a family history, long-term steroid use or an early menopause.
Screening programmes
There is no routine screening test for locomotor problems in general. Some people at higher risk of weak bones may be offered a bone density scan, and some health services invite older adults for a falls-risk review. Ask your doctor whether any of these apply to you.
Complications
If left untreated
- Long-lasting pain that affects sleep, mood and daily life
- Stiffness and loss of movement in a joint
- Muscle weakness and wasting from not using the affected area
- Joint damage that gets worse over time
- More falls, which can lead to broken bones
- Difficulty with work, caring responsibilities or hobbies
- Loss of independence in daily tasks such as dressing or climbing stairs
Long-term outlook
For most people, muscle and joint problems improve with time, rest and the right support. Many long-term conditions can be managed well with activity, physiotherapy and medicines when needed, and joint replacement surgery helps a great many people return to the things they love. The earlier you get advice, the more options you have — so it is worth speaking to your doctor or physiotherapist rather than waiting.
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Health guidance differs by country and region. This page is general education and may not match the guidelines, medicines, or practice where you live. Discuss your concerns with your own doctor or healthcare provider, and follow local guidance where it exists.
Important notice This information is for educational purposes only. It does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider about your specific situation. If you are experiencing a medical emergency, call your local emergency services immediately.
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Sources and guidance
No guideline names this topic
No health guideline or clinical chapter that names this exact topic is cited here. This page is for general education and information only. It is not a diagnosis, a treatment plan, or personal medical advice. Check with your own doctor and follow their advice. If symptoms are severe, sudden, or worrying, get medical care promptly, and call your local emergency number in an emergency. Ruqelo LLC is not responsible for medical or legal outcomes from decisions based on this information.
Last updated: October 24, 2026
Educational note: This information is for education only and is not a diagnosis.
Use it to support, not replace, advice from a licensed clinician.
If symptoms are severe, worsening, or urgent, call your local emergency number or seek emergency care.
Guidance may differ by country or region. Confirm local recommendations with a qualified healthcare provider.