Negative pressure wound therapy
Informed by recognized medical guidance
Overview
Negative pressure wound therapy (NPWT) is a treatment that uses a sealed dressing connected to a vacuum pump to gently pull fluid and infection out of a wound. This helps the wound heal faster by reducing swelling, keeping it clean, and encouraging new tissue growth.
Key facts
- NPWT is also called vacuum-assisted closure or VAC therapy.
- It is used for wounds that are slow to heal, such as pressure sores, diabetic foot ulcers, or surgical wounds that have opened up.
- The therapy is usually done in hospital or at home with a portable device under medical supervision.
Negative pressure wound therapy is a standard treatment used in many hospitals worldwide. It is not unusual for people with complex or slow-healing wounds.
NPWT is used for people of any age who have a wound that is not healing well. It is especially common in people with diabetes, poor circulation, or after certain surgeries.
Symptoms
- Sudden heavy bleeding from the wound
- Signs of a severe allergic reaction (trouble breathing, swelling of face or throat)
- Severe chest pain or trouble breathing while on NPWT (which could be a rare sign of a blood clot)
- ⚠Fever or chills along with wound changes
- ⚠Wound that becomes very painful, hot, or produces a bad smell
- ⚠Dressing comes off or machine alarms repeatedly
Common symptoms
- Slow wound healing despite standard wound care
- Wound with drainage (fluid or pus)
- Swelling or redness around the wound
Symptoms in children
- Wound that leaks fluid or looks infected
- Child may complain of pain or tenderness around the wound
Symptoms in older adults
- Wound that does not close or improves very slowly
- Skin around the wound may be thin or fragile
- Increased risk of infection due to lower immunity
Causes
Main causes
- Slow-healing wounds due to diabetes, poor blood flow, or pressure injuries
- Open surgical wounds that need help to close
- Infected wounds that need drainage
Risk factors
- Diabetes
- Obesity
- Smoking
- Poor nutrition
- Immobility or being bedridden
- Weakened immune system (from chemotherapy or medications)
- Advanced age
When to see a doctor
See a doctor urgently if:
- Any sign of wound infection (pus, redness spreading, fever)
- Dressing falls off or vacuum seal breaks repeatedly
- Pain that gets worse instead of better
Book a routine appointment if:
- If you have a wound that is not healing after several weeks of standard care
- To ask if NPWT might be an option for your wound
Diagnosis
There is no single test for NPWT. Your doctor or wound care nurse will examine your wound, review your medical history, and decide if NPWT is suitable. They may check your blood flow or take a swab to look for infection.
Tests that may be done
- Physical examination of the wound
- Blood tests to check for infection or nutritional status
- Imaging (like ultrasound) to see deeper tissues if needed
What to expect at your appointment
If NPWT is recommended, a nurse or doctor will clean the wound, place a foam or gauze dressing over it, seal it with a clear film, and attach a tube to a small pump that creates suction. The dressing is usually changed every 2-3 days. The pump may run continuously or intermittently. You will be shown how to care for it at home if needed.
Treatment
Negative pressure wound therapy is one part of wound care. It is often combined with cleaning, infection control, and good nutrition. The goal is to keep the wound moist, reduce fluid, and stimulate growth of new tissue.
Self-care at home
- Keep the dressing sealed and the machine running as instructed
- Report any alarms or changes in the wound to your healthcare team immediately
- Eat a healthy diet rich in protein and vitamins to support healing
- Do not remove the dressing yourself – it must be changed by a professional
Medical treatments
Your doctor may prescribe antibiotics if there is an infection. They may also use special wound dressings or gels under the NPWT dressing. Pain medication can be given to keep you comfortable during dressing changes. If the wound is very deep or has dead tissue, surgery may be needed to remove it before starting NPWT.
When is surgery considered?
In some cases, surgery is needed to clean the wound (debridement) before NPWT can be most effective. NPWT itself is not a surgery, but it may be used before or after a surgical wound closure.
Living with this condition
You may need to carry the portable NPWT pump with you. It is small and can be worn on a belt or shoulder strap. You can do most daily activities, but avoid getting the dressing wet. Check with your team before showering or bathing.
Lifestyle tips
- Avoid smoking, as it slows wound healing
- Keep all follow-up appointments for dressing changes
- Monitor the machine and wound daily for any problems
Diet and exercise
Eat plenty of protein (like lean meat, beans, eggs) and vitamin C (found in fruits and vegetables) to help tissue repair. Gentle movement, as advised by your doctor, can improve blood flow, but avoid putting pressure on the wound.
Mental health and emotional wellbeing
Living with a chronic wound and using NPWT can feel frustrating or isolating. It is normal to feel anxious or low. Talk to your healthcare team or a counsellor if you need emotional support. You are not alone.
Prevention
You may not be able to prevent the need for NPWT, but you can reduce your risk of slow-healing wounds by managing underlying conditions like diabetes, eating well, staying active, and not smoking. If you have a wound, getting early treatment can sometimes prevent the need for more advanced therapies.
Complications
If left untreated
- Wound may become larger or deeper
- Infection can spread to nearby tissue or bone
- Prolonged pain and delayed healing
Long-term outlook
With proper use, negative pressure wound therapy greatly improves healing for many people. Most wounds get smaller and close faster. Although it can take weeks or months, the outlook is positive, especially when combined with good overall care.
Find support
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Always verify with your doctor
Health guidelines vary by country and region. The information in this article is based on international clinical guidelines but may not reflect the specific guidelines, medications, or practices in your country. Always discuss your health concerns with your own doctor or healthcare provider, and refer to your local national health guidelines where available.
Important notice This information is for educational purposes only. It does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider about your specific situation. If you are experiencing a medical emergency, call your local emergency services immediately.
Related conditions
Sources and guidance
This article is educational and is prepared with reference to recognized health information and clinical guidance sources where available. Specific source links may vary by topic.
Last updated: July 16, 2026
Educational note: This information is for education only and is not a diagnosis.
Use it to support, not replace, advice from a licensed clinician.
If symptoms are severe, worsening, or urgent, call your local emergency number or seek emergency care.
Guidance may differ by country or region. Confirm local recommendations with a qualified healthcare provider.