16398 Quantitative Sudomotor Axon Reflex Test Qsart
Overview
QSART is a special test that checks the small nerves that control sweating. These nerves are part of the autonomic nervous system, the body system that manages automatic jobs like heart rate, blood pressure, digestion, and sweating. During QSART, small electrodes are placed on the skin and a mild electrical current stimulates sweat glands. The test measures how much sweat comes out. It helps your healthcare provider look for small nerve fiber damage or autonomic nervous system problems. QSART is a test, not a disease.
Key facts
- QSART checks the small nerves that control sweating and helps your care team understand symptoms like dizziness on standing, fainting, or unusual sweating.
- The test uses small electrodes on the skin. It does not use needles and is usually not painful, though you may feel mild warmth or tingling.
- QSART is done in a specialty clinic and often takes about 1 to 1.5 hours, including preparation and rest.
QSART is not a routine test. It is used in specialized autonomic testing centers when a doctor needs more information about small nerve fibers or the autonomic nervous system.
QSART can be done in children and adults. It is used for people who have symptoms that might involve small nerves or the autonomic nervous system, such as dizziness on standing, fainting, abnormal sweating, burning feet, or heat intolerance.
Symptoms
- Call your local emergency number immediately if you faint and do not wake up quickly, or if you have a seizure.
- Call emergency services for fainting with chest pain, trouble breathing, a very fast or irregular heartbeat, or bluish lips.
- Call emergency services for sudden weakness or numbness on one side of the body, trouble speaking, confusion, or a sudden severe headache.
- Call emergency services if someone becomes very confused, extremely hot with little or no sweating, or collapses after being in heat.
- ⚠You faint for the first time, even if you wake up quickly. Get same-day medical advice.
- ⚠You have repeated dizziness or near-fainting that is new or getting worse.
- ⚠You cannot sweat and feel overheated, very thirsty, or unwell in hot weather.
- ⚠You have a foot wound, infection, or new severe pain and numbness in the feet.
- ⚠You have severe constipation with vomiting or a bloated, painful abdomen.
Common symptoms
- Dizziness or light-headedness when standing up
- Fainting or near-fainting
- Sweating too much or too little, especially in the feet or legs
- Burning, tingling, numbness, or pain in the feet or hands
- Feeling very sensitive to heat or unable to cool down normally
- Dry eyes, dry mouth, constipation, or bladder problems
- Feeling tired or short of breath with activity more than expected
Symptoms in children
- Dizziness or fainting, especially when standing up quickly
- Poor sweating or heat intolerance during play or sports
- Trouble describing burning or tingling feelings in the feet or hands
- Stomach or bladder symptoms that are hard to explain
- Feeling unusually tired or weak with activity
Symptoms in older adults
- Dizziness or falls when standing up
- Dry skin or reduced sweating, which can make heat feel worse
- Symptoms that may be mistaken for normal aging or side effects of other health conditions
- Burning or numb feet, which can raise the risk of foot injuries
- Bladder or bowel changes that need review
Causes
Main causes
- QSART is a test, not a condition, so it does not have causes. It is used when a healthcare provider suspects a problem with small nerve fibers or the autonomic nervous system.
- Possible causes of small fiber or autonomic nerve problems include diabetes, some autoimmune conditions, amyloidosis, infections, low vitamin levels, inherited nerve disorders, alcohol misuse, and exposure to some medicines or toxins.
- Sometimes no clear cause is found. The test results help your care team decide what to check next.
Risk factors
- Diabetes or prediabetes
- Past chemotherapy or other treatments that can affect nerves
- Heavy alcohol use
- Autoimmune conditions, such as lupus or Sjogren syndrome
- Family history of nerve or autonomic disorders
- Older age, though younger people can be affected too
- Exposure to toxins or certain medicines that can harm nerves
When to see a doctor
See a doctor urgently if:
- You faint or nearly faint and injure yourself.
- You have new chest pain, trouble breathing, or a very fast or irregular heartbeat.
- You have sudden weakness, numbness, confusion, or trouble speaking.
- You show signs of overheating, such as confusion, very hot skin, or collapse after heat exposure.
- You have a foot wound or infection and you also have numb feet.
Book a routine appointment if:
- You have repeated dizziness or light-headedness when standing.
- You have unusual sweating, either too much or too little, that bothers you.
- You have burning, tingling, or numbness in the feet or hands.
- You feel unusually heat intolerant or have trouble cooling down.
- You have bladder, bowel, or digestion symptoms that your provider thinks may be linked to nerve or autonomic problems.
Diagnosis
QSART is one part of an autonomic evaluation. Your healthcare provider will ask about your symptoms, health history, and medicines, and do a physical exam. They may order QSART along with other tests to see how your small nerves and autonomic nervous system are working. The results help your provider look for a cause and plan next steps. QSART alone does not diagnose a specific disease.
Tests that may be done
- QSART, which measures sweat response after mild electrical stimulation
- Other autonomic tests, such as tilt-table testing or heart rate and blood pressure checks with position changes
- Thermoregulatory sweat test, which looks at sweating over larger areas of the body
- Blood tests to check for diabetes, vitamin levels, thyroid problems, or autoimmune conditions
- Nerve conduction studies or electromyography, which check larger nerves
- Skin biopsy, which can look at small nerve fibers in a small sample of skin
- Imaging or other tests if your provider needs to check for another condition
What to expect at your appointment
You may be asked to avoid smoking, caffeine, heavy exercise, or lotions on the skin for a few hours before the test. Ask your provider whether any of your medicines need to be adjusted; do not change medicines on your own. During QSART, you will lie down and small electrodes will be placed on your arm or leg. You may feel mild warmth, tingling, or pulsing. The test is usually well tolerated. Afterward, you can often go back to normal activities. Results are reviewed later by your care team.
Treatment
There is no treatment for QSART itself because it is a test. Treatment focuses on the cause of your symptoms if one is found, and on helping you feel better day to day.
Self-care at home
- Drink enough fluid, especially in hot weather or when you feel light-headed.
- Stand up slowly and sit or lie down if you feel dizzy.
- Use cooling measures, such as fans, cool showers, and loose clothing, if heat bothers you.
- Check your feet daily for cuts, blisters, or redness, especially if you have numbness.
- Keep a simple symptom diary to share with your care team.
- Ask your provider before making big changes to salt intake, exercise, or daily routines.
Medical treatments
Your healthcare provider will treat any underlying condition they find and manage symptoms with a plan that fits you. This may include changes to medicines that affect blood pressure or sweating, but only with your provider's advice. Other options can include physical therapy, compression stockings, cooling strategies, and help with bowel or bladder symptoms. There are no medicines that treat QSART itself.
When is surgery considered?
Surgery is not part of QSART. If another condition is found, surgery is only considered when it is the right treatment for that condition.
Living with this condition
Living with nerve or autonomic symptoms often means planning ahead. You may need to pace activities, avoid very hot places, and take breaks when you feel dizzy or tired. A clear plan from your care team can make daily life safer and more predictable.
Lifestyle tips
- Keep a regular sleep routine and avoid becoming overtired.
- Rise slowly from bed or a chair, and flex your feet and hands before standing.
- Avoid long hot showers, saunas, or very hot rooms if heat makes you feel unwell.
- Wear well-fitting shoes and check your feet every day.
- Carry water and a cool pack when you are out in warm weather.
- Ask your provider about safe exercise and how to pace yourself.
Diet and exercise
Your provider may suggest more fluid and salt if you have low blood pressure on standing, but only if it is safe for you. Gentle exercise, such as swimming or recumbent biking, may help some people. Avoid very hot or intense workouts until you know how your body responds. A dietitian or your care team can help you build a plan that fits your health needs.
Mental health and emotional wellbeing
Symptoms like dizziness, fainting, or pain can be worrying and can affect work, school, and social life. It is normal to feel anxious or low at times. Tell your healthcare provider if these feelings are building up. If you ever have thoughts of harming yourself, contact your local crisis service or emergency services right away.
Prevention
You cannot prevent QSART because it is a test. Some causes of nerve damage may be prevented or slowed by managing diabetes, limiting alcohol, avoiding toxins, and treating underlying health conditions. Ask your provider what steps are right for you.
Vaccines
Vaccines are not related to QSART or the nerve and sweating problems it checks. Keep up with routine vaccines as advised by your healthcare provider.
Screening programmes
QSART is not a screening test for the general public. It is used when a person has symptoms that suggest a small nerve fiber or autonomic problem. Your provider will tell you if testing is needed.
Complications
If left untreated
- Falls and injuries from fainting or dizziness
- Heat illness or overheating if sweating is reduced
- Foot wounds or infections if numbness is present
- Ongoing pain, burning, or discomfort in the feet or hands
- Bladder, bowel, or digestion problems that affect daily life
Long-term outlook
The outlook depends on the cause of your symptoms. QSART gives your care team helpful information so they can choose the right next steps. Many small nerve and autonomic problems can be managed with a clear plan, and most people can improve their safety and comfort over time.
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Always verify with your doctor
Health guidance differs by country and region. This page is general education and may not match the guidelines, medicines, or practice where you live. Discuss your concerns with your own doctor or healthcare provider, and follow local guidance where it exists.
Important notice This information is for educational purposes only. It does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider about your specific situation. If you are experiencing a medical emergency, call your local emergency services immediately.
Related conditions
Sources and guidance
No guideline names this topic
No health guideline or clinical chapter that names this exact topic is cited here. This page is for general education and information only. It is not a diagnosis, a treatment plan, or personal medical advice. Check with your own doctor and follow their advice. If symptoms are severe, sudden, or worrying, get medical care promptly, and call your local emergency number in an emergency. Ruqelo LLC is not responsible for medical or legal outcomes from decisions based on this information.
Last updated: November 3, 2026
Educational note: This information is for education only and is not a diagnosis.
Use it to support, not replace, advice from a licensed clinician.
If symptoms are severe, worsening, or urgent, call your local emergency number or seek emergency care.
Guidance may differ by country or region. Confirm local recommendations with a qualified healthcare provider.