Diagnostics·Diagnostics
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Amylase and lipase are two enzymes (proteins that help with digestion) made by your pancreas. An amylase test and a lipase test measure the amount of these enzymes in your blood. High levels can signal that your pancreas is inflamed or damaged. The tests help doctors find the cause of belly pain and other symptoms.
Key facts
These tests are very common. Any healthcare provider can order them when someone has belly pain, especially if pancreatitis is suspected.
The tests are done in people of all ages who have symptoms like severe upper belly pain, nausea, or vomiting. They are especially used in adults with risk factors such as gallstones or heavy alcohol use.
A doctor will listen to your symptoms, examine your belly, and order a blood test to measure amylase and lipase levels. Often they will also check other things like liver function, triglycerides, and a complete blood count. Imaging tests like an ultrasound or CT scan may be done to look at the pancreas and gallbladder.
Treatment depends on the cause of the abnormal test results. If high amylase and lipase are due to acute pancreatitis, the focus is on resting the pancreas, managing pain, and preventing complications. If gallstones are the cause, surgery to remove the gallbladder may be needed after the inflammation settles.
Doctors may provide intravenous (IV) fluids to prevent dehydration and pain relievers through a drip or injection. If you are unable to eat, you may receive nutrition through a tube. Antibiotics are not given unless an infection is confirmed. For high triglycerides, medicines to lower them may be prescribed. The specific medication will depend on your overall health and should be discussed with your healthcare provider.
After an episode of pancreatitis, you will need to follow a low‑fat diet, avoid alcohol, and not smoke. Many people feel better and return to normal activities within a few days to a week for mild cases. Chronic pancreatitis may require ongoing care, including enzyme supplements and management of pain.
A low‑fat, high‑protein diet is often recommended. Good choices include lean chicken, fish, beans, rice, and vegetables. Avoid fried foods, butter, creamy sauces, and fatty cuts of meat. Gentle exercise like walking can help with recovery, but strenuous activities may need to be avoided until you feel stronger.
Not all causes can be prevented, but you can lower your risk of pancreatitis. The most important steps are to avoid heavy alcohol use, maintain a healthy weight, and treat gallstones or high triglycerides early. If you have a family history, talk to your doctor about monitoring your levels.
Routine screening for amylase and lipase in people without symptoms is not recommended. However, if you have risk factors like a strong family history of pancreatitis or known high triglycerides, your doctor may check your levels occasionally.
Most people with acute pancreatitis recover fully with treatment. The outlook depends on the cause. If you stop drinking alcohol and manage gallstones, the chance of recurrence is low. Chronic pancreatitis is a long‑term condition, but with good care – including diet changes, medicine, and avoiding triggers – most people can lead a full and active life. Your doctor will work with you to create a plan that keeps you healthy.
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Always verify with your doctor
Health guidelines vary by country and region. The information in this article is based on international clinical guidelines but may not reflect the specific guidelines, medications, or practices in your country. Always discuss your health concerns with your own doctor or healthcare provider, and refer to your local national health guidelines where available.
Important notice This information is for educational purposes only. It does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider about your specific situation. If you are experiencing a medical emergency, call your local emergency services immediately.
This article is educational and is prepared with reference to recognized health information and clinical guidance sources where available. Specific source links may vary by topic.
Last updated: July 8, 2026
Educational note: This information is for education only and is not a diagnosis.
Use it to support, not replace, advice from a licensed clinician.
If symptoms are severe, worsening, or urgent, call your local emergency number or seek emergency care.
The blood test is taken from a vein in your arm, just like any routine blood draw. It takes only a few minutes. You may need to fast (not eat or drink) for 8 to 12 hours before the test, depending on your doctor's instructions. The results usually come back within a few hours to a day. Your doctor will explain what the numbers mean and what to do next.
If gallstones are blocking the pancreatic duct, a procedure called ERCP (endoscopic retrograde cholangiopancreatography) may be done to remove them. Later, a cholecystectomy (removal of the gallbladder) may be recommended to prevent future attacks. Surgery is also considered for complications like an infected fluid collection (pseudocyst) that does not heal on its own.
Living with a chronic health condition can be stressful and worrying. You may feel anxious about future attacks or frustrated with diet restrictions. It is normal to have these feelings. Talk to your doctor or a counsellor if they become overwhelming.