Diagnostics·Diagnostics
Direct Coombs test
Informed by recognized medical guidance
Overview
The Direct Coombs test (also called the direct antiglobulin test) is a blood test that checks for antibodies attached to your red blood cells. These antibodies can cause your immune system to attack and destroy your own red blood cells, leading to a condition called hemolytic anemia.
Key facts
- The test looks for proteins called antibodies that are stuck to the surface of red blood cells.
- A positive result may mean your body is destroying its own red blood cells too quickly.
- The test is often used to help diagnose hemolytic anemia or to check for blood transfusion reactions.
- It is a simple blood draw and does not require any special preparation.